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These microorganisms are responsible for producing favorable microbial metabolites such as short-chain fatty acids (SCFAs), tryptophan derivatives, and secondary bile acids, among other products, playing crucial roles in regulating immunity, reducing inflammation, and maintaining gut homeostasis [37]

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Body weight considerations The Phase 2 clinical trial used fixed doses regardless of body weight

200 nM) to evaluate mitochondrial membrane potential, and MitoSOX (5 M) to detect mitochondrial superoxide levels (all probes sourced from Molecular Probes)

Phase 3 results for retatrutide